Chapter 8 Ras: Processor of Vital Signals

Dennis W. Stacey

doi:10.1016/S1569-254X(96)80010-0

Chapter 8 Ras: Processor of Vital Signals

Dennis W. Stacey

Cleveland Clinic Foundation

Research output: Contribution to journal › Article › peer-review

Abstract

The pivotal role of Ras as a transducer of vital signals is well established. As such, aberrant Ras signaling is associated with cancer, neurofibromatosis, and Alzheimer's disease. This realization could make detection of mutated ras a useful diagnostic and prognostic tool. Exploiting the biochemical properties of Ras has made interfering with Ras activity a potential clinical option and dissection of the relative contribution of each signaling pathway emanating from Ras will certainly provide additional targets for clinical intervention. © 1996 Elsevier Inc. All rights reserved.

Original language	American English
Journal	Advances in Oncobiology
Volume	1
DOIs	https://doi.org/10.1016/S1569-254X(96)80010-0
State	Published - Dec 1 1996
Externally published	Yes

Disciplines

Biology

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https://doi.org/10.1016/S1569-254X(96)80010-0

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abstract = " The pivotal role of Ras as a transducer of vital signals is well established. As such, aberrant Ras signaling is associated with cancer, neurofibromatosis, and Alzheimer's disease. This realization could make detection of mutated ras a useful diagnostic and prognostic tool. Exploiting the biochemical properties of Ras has made interfering with Ras activity a potential clinical option and dissection of the relative contribution of each signaling pathway emanating from Ras will certainly provide additional targets for clinical intervention. {\textcopyright} 1996 Elsevier Inc. All rights reserved.",

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AB - The pivotal role of Ras as a transducer of vital signals is well established. As such, aberrant Ras signaling is associated with cancer, neurofibromatosis, and Alzheimer's disease. This realization could make detection of mutated ras a useful diagnostic and prognostic tool. Exploiting the biochemical properties of Ras has made interfering with Ras activity a potential clinical option and dissection of the relative contribution of each signaling pathway emanating from Ras will certainly provide additional targets for clinical intervention. © 1996 Elsevier Inc. All rights reserved.

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Chapter 8 Ras: Processor of Vital Signals

Abstract

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