Ultrafast Flow Quantification With Segmented K-Space Magnetic Resonance Phase Velocity Mapping

Haosen Zhang; Sandra S. Halliburton; James R. Moore; Orlando P. Simonetti; Paulo R. Schvartzman; Richard D. White; George P. Chatzimavroudis

doi:10.1114/1.1433489

Ultrafast Flow Quantification With Segmented K-Space Magnetic Resonance Phase Velocity Mapping

Haosen Zhang, Sandra S. Halliburton, James R. Moore, Orlando P. Simonetti, Paulo R. Schvartzman, Richard D. White, George P. Chatzimavroudis

Research output: Contribution to journal › Article › peer-review

Abstract

Magnetic resonance (MR) phase - velocity mapping (PVM) is routinely being used clinically to measure blood flow velocity . Conventional nonsegmented PVM is accurate but relatively slow (3–5 min per measurement). Ultrafast k - space segmented PVM offers much shorter acquisitions (on the order of seconds instead of minutes). The aim of this study was to evaluate the accuracy of segmented PVM in quantifying flow from through-plane velocity measurements. Experiments were performed using four straight tubes (inner diameter of 5.6–26.2 mm), under a variety of steady (1.7–200 ml/s) and pulsatile (6–90 ml/cycle) flow conditions. Two different segmented PVM schemes were tested, one with five k - space lines per segment and one with nine lines per segment. Results showed that both segmented sequences provided very accurate flow quantification (errorsflow conditions, even under turbulent flow conditions. This agreement was confirmed via regression analysis. Further statistical analysis comparing the flow data from the segmented PVM techniques with (i) the data from the nonsegmented technique and (ii) the true flow values showed no significant difference (all p values&gg;0.05). Preliminary flow measurements in the ascending aorta of two human subjects using the nonsegmented sequence and the segmented sequence with nine lines per segment showed very close agreement. The results of this study suggest that ultrafast PVM has great potential to measure blood velocity and quantify blood flow clinically. © 2002 Biomedical Engineering Society.

Original language	American English
Journal	Annals of Biomedical Engineering
Volume	30
DOIs	https://doi.org/10.1114/1.1433489
State	Published - Jan 1 2002

Keywords

MRI
Turbo gradient echo
Segmented k-space
Blood flow
Velocimetry
Pulsatile flow
Turbulent flow

Disciplines

Biochemical and Biomolecular Engineering
Biomedical Engineering and Bioengineering

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http://dx.doi.org/10.1114/1.1433489

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@article{09f6177642ec4f97937aa431646d1788,

title = "Ultrafast Flow Quantification With Segmented K-Space Magnetic Resonance Phase Velocity Mapping",

abstract = " Magnetic resonance (MR) phase - velocity mapping (PVM) is routinely being used clinically to measure blood flow velocity . Conventional nonsegmented PVM is accurate but relatively slow (3\–5 min per measurement). Ultrafast k - space segmented PVM offers much shorter acquisitions (on the order of seconds instead of minutes). The aim of this study was to evaluate the accuracy of segmented PVM in quantifying flow from through-plane velocity measurements. Experiments were performed using four straight tubes (inner diameter of 5.6\–26.2 mm), under a variety of steady (1.7\–200 ml/s) and pulsatile (6\–90 ml/cycle) flow conditions. Two different segmented PVM schemes were tested, one with five k - space lines per segment and one with nine lines per segment. Results showed that both segmented sequences provided very accurate flow quantification (errorsflow conditions, even under turbulent flow conditions. This agreement was confirmed via regression analysis. Further statistical analysis comparing the flow data from the segmented PVM techniques with (i) the data from the nonsegmented technique and (ii) the true flow values showed no significant difference (all p values\&gg;0.05). Preliminary flow measurements in the ascending aorta of two human subjects using the nonsegmented sequence and the segmented sequence with nine lines per segment showed very close agreement. The results of this study suggest that ultrafast PVM has great potential to measure blood velocity and quantify blood flow clinically. \© 2002 Biomedical Engineering Society. ",

keywords = "MRI, Turbo gradient echo, Segmented k-space, Blood flow, Velocimetry, Pulsatile flow, Turbulent flow",

author = "Haosen Zhang and Halliburton, \{Sandra S.\} and Moore, \{James R.\} and Simonetti, \{Orlando P.\} and Schvartzman, \{Paulo R.\} and White, \{Richard D.\} and Chatzimavroudis, \{George P.\}",

note = "Zhang, H., Halliburton, S. S., Moore, J. R., Simonetti, O. P., Schvartzman, P. R., White, R. D., , \& Chatzimavroudis, G. P. (2002). Ultrafast Flow Quantification With Segmented k-Space Magnetic Resonance Phase Velocity Mapping. Annals of Biomedical Engineering, 30(1), 120-128.",

year = "2002",

month = jan,

day = "1",

doi = "10.1114/1.1433489",

language = "American English",

volume = "30",

journal = "Annals of Biomedical Engineering",

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TY - JOUR

T1 - Ultrafast Flow Quantification With Segmented K-Space Magnetic Resonance Phase Velocity Mapping

AU - Zhang, Haosen

AU - Halliburton, Sandra S.

AU - Moore, James R.

AU - Simonetti, Orlando P.

AU - Schvartzman, Paulo R.

AU - White, Richard D.

AU - Chatzimavroudis, George P.

N1 - Zhang, H., Halliburton, S. S., Moore, J. R., Simonetti, O. P., Schvartzman, P. R., White, R. D., , & Chatzimavroudis, G. P. (2002). Ultrafast Flow Quantification With Segmented k-Space Magnetic Resonance Phase Velocity Mapping. Annals of Biomedical Engineering, 30(1), 120-128.

PY - 2002/1/1

Y1 - 2002/1/1

N2 - Magnetic resonance (MR) phase - velocity mapping (PVM) is routinely being used clinically to measure blood flow velocity . Conventional nonsegmented PVM is accurate but relatively slow (3–5 min per measurement). Ultrafast k - space segmented PVM offers much shorter acquisitions (on the order of seconds instead of minutes). The aim of this study was to evaluate the accuracy of segmented PVM in quantifying flow from through-plane velocity measurements. Experiments were performed using four straight tubes (inner diameter of 5.6–26.2 mm), under a variety of steady (1.7–200 ml/s) and pulsatile (6–90 ml/cycle) flow conditions. Two different segmented PVM schemes were tested, one with five k - space lines per segment and one with nine lines per segment. Results showed that both segmented sequences provided very accurate flow quantification (errorsflow conditions, even under turbulent flow conditions. This agreement was confirmed via regression analysis. Further statistical analysis comparing the flow data from the segmented PVM techniques with (i) the data from the nonsegmented technique and (ii) the true flow values showed no significant difference (all p values&gg;0.05). Preliminary flow measurements in the ascending aorta of two human subjects using the nonsegmented sequence and the segmented sequence with nine lines per segment showed very close agreement. The results of this study suggest that ultrafast PVM has great potential to measure blood velocity and quantify blood flow clinically. © 2002 Biomedical Engineering Society.

AB - Magnetic resonance (MR) phase - velocity mapping (PVM) is routinely being used clinically to measure blood flow velocity . Conventional nonsegmented PVM is accurate but relatively slow (3–5 min per measurement). Ultrafast k - space segmented PVM offers much shorter acquisitions (on the order of seconds instead of minutes). The aim of this study was to evaluate the accuracy of segmented PVM in quantifying flow from through-plane velocity measurements. Experiments were performed using four straight tubes (inner diameter of 5.6–26.2 mm), under a variety of steady (1.7–200 ml/s) and pulsatile (6–90 ml/cycle) flow conditions. Two different segmented PVM schemes were tested, one with five k - space lines per segment and one with nine lines per segment. Results showed that both segmented sequences provided very accurate flow quantification (errorsflow conditions, even under turbulent flow conditions. This agreement was confirmed via regression analysis. Further statistical analysis comparing the flow data from the segmented PVM techniques with (i) the data from the nonsegmented technique and (ii) the true flow values showed no significant difference (all p values&gg;0.05). Preliminary flow measurements in the ascending aorta of two human subjects using the nonsegmented sequence and the segmented sequence with nine lines per segment showed very close agreement. The results of this study suggest that ultrafast PVM has great potential to measure blood velocity and quantify blood flow clinically. © 2002 Biomedical Engineering Society.

KW - MRI

KW - Turbo gradient echo

KW - Segmented k-space

KW - Blood flow

KW - Velocimetry

KW - Pulsatile flow

KW - Turbulent flow

UR - https://engagedscholarship.csuohio.edu/encbe_facpub/76

U2 - 10.1114/1.1433489

DO - 10.1114/1.1433489

M3 - Article

VL - 30

JO - Annals of Biomedical Engineering

JF - Annals of Biomedical Engineering

ER -

Ultrafast Flow Quantification With Segmented K-Space Magnetic Resonance Phase Velocity Mapping

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